Central effect of atrial natriuretic polypeptide on angiotensin II-stimulated vasopressin secretion in concious rats

Takayuki Yamada, Kazuwa Nakao, Narito Morii, Hiroshi Itoh, Shozo Shiono, Makoto Sakamoto, Akira Sugawara, Yoshihiko Saito, Hideto Ohno, Akira Kanai, Goro Katsuura, Masami Eigyo, Akira Matsushita, Hiroo Imura

研究成果: Article査読

87 被引用数 (Scopus)

抄録

The effect of intracerebroventricular (i.c.v.) treatment of α-human atrial natriuretic polypeptide on the vasopressin secretion induced by i.c.v. injection of angiotensin II was studied in conscious, unrestrained rats. Pretreatment of α-human atrial natriuretic polypeptide (5 μg) significantly inhibited the angiotensin II (100 ng)-stimulated vasopressin secretion. This result suggests that atrial natriuretic polypeptide plays regulatory roles in vasopressin secretion in the central nervous system.

本文言語English
ページ(範囲)453-456
ページ数4
ジャーナルEuropean journal of pharmacology
125
3
DOI
出版ステータスPublished - 1986 6 24
外部発表はい

ASJC Scopus subject areas

  • Pharmacology

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