Centrifugal microfluidic system for multistep assay using small amount of various samples

H. Hasegawa, T. Teshima, H. Onoe, S. Takeuchi

研究成果: Article査読

2 被引用数 (Scopus)

抄録

This paper describes a centrifuge-based dynamic microarray system using small amount of samples for application in multistep assays. The system uses meander-shaped microchannel and arrayed trapping spots to trap the samples with fluid stream generated by centrifugal force. Producing an array of samples suspended in only 1 μl of solution is achieved in 3 s with this system. After the loading solution is introduced, air is infused into the microchannel, keeping the sample and loading solution at the trapping spot. This air infusion allows us to immobilize and isolate the trapped samples suspended in the loading solution. In addition, the solution around the trapped sample can be repeatedly exchanged by introducing another solution. This system is applicable for multistep assays using small amount of rare samples.

本文言語English
ページ(範囲)281-286
ページ数6
ジャーナルSensors and Actuators, B: Chemical
195
DOI
出版ステータスPublished - 2014 5
外部発表はい

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 器械工学
  • 凝縮系物理学
  • 表面、皮膜および薄膜
  • 金属および合金
  • 電子工学および電気工学
  • 材料化学

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