Changes in choline acetyltranferase distribution in the cervical spinal cord after reversible cervical spinal cord injury

Masaya Nakamura, Y. Fujimura, Y. Yato, M. Watanabe, Y. Iwamoto

研究成果: Article

4 引用 (Scopus)

抄録

Reversible spinal cord injury (SCI) at C6 level in rats, produced by the weight-placed method, resulted in a severe motor functional deficit initially, followed by a gradual recovery. During the recovery, choline acetyltransferase (CAT) distribution in the cervical spinal cord was investigated at 2, 4, 7, 14 and 28 days after the injury by quantitative immunohistochemistry with a fluorescence microphotometry system. At C6 level, the flourescence intensity of the ventrolateral anterior horn (VLAH), which reflected the concentration of CAT, decreased to approximately 50% of that of the sham-operated group at 2 days. It then recovered to 60% at 4 days after the injury, and remained unchanged thereafter. Fluorescence intensities in VLAH at C4-5 and C7-8 levels decreased to approximately 60-70% at 2 days after the injury, but it recovered and increased to 110-130% thereafter.

元の言語English
ページ(範囲)752-758
ページ数7
ジャーナルParaplegia
32
発行部数11
出版物ステータスPublished - 1994

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Choline
Spinal Cord Injuries
Choline O-Acetyltransferase
Horns
Wounds and Injuries
Fluorescence
Immunohistochemistry
Weights and Measures
Cervical Cord

ASJC Scopus subject areas

  • Clinical Neurology

これを引用

Changes in choline acetyltranferase distribution in the cervical spinal cord after reversible cervical spinal cord injury. / Nakamura, Masaya; Fujimura, Y.; Yato, Y.; Watanabe, M.; Iwamoto, Y.

:: Paraplegia, 巻 32, 番号 11, 1994, p. 752-758.

研究成果: Article

Nakamura, Masaya ; Fujimura, Y. ; Yato, Y. ; Watanabe, M. ; Iwamoto, Y. / Changes in choline acetyltranferase distribution in the cervical spinal cord after reversible cervical spinal cord injury. :: Paraplegia. 1994 ; 巻 32, 番号 11. pp. 752-758.
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AU - Yato, Y.

AU - Watanabe, M.

AU - Iwamoto, Y.

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AB - Reversible spinal cord injury (SCI) at C6 level in rats, produced by the weight-placed method, resulted in a severe motor functional deficit initially, followed by a gradual recovery. During the recovery, choline acetyltransferase (CAT) distribution in the cervical spinal cord was investigated at 2, 4, 7, 14 and 28 days after the injury by quantitative immunohistochemistry with a fluorescence microphotometry system. At C6 level, the flourescence intensity of the ventrolateral anterior horn (VLAH), which reflected the concentration of CAT, decreased to approximately 50% of that of the sham-operated group at 2 days. It then recovered to 60% at 4 days after the injury, and remained unchanged thereafter. Fluorescence intensities in VLAH at C4-5 and C7-8 levels decreased to approximately 60-70% at 2 days after the injury, but it recovered and increased to 110-130% thereafter.

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KW - Reversible cervical spinal cord injury in rats

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