Changes in the expression of cytochrome P450 genes in hemin-induced differentiated K562 cells

Medicine & Life Sciences

• Hemin 100%
• K562 Cells 88%
• Cytochrome P-450 CYP3A 84%
• Cytochrome P-450 Enzyme System 72%
• Genes 29%
• Leukemia, Erythroblastic, Acute 24%
• Cytochrome P-450 CYP2E1 24%
• Cytochrome P-450 CYP1A1 23%
• Gene Expression 22%
• Cell Line 22%
• Midazolam 20%
• Xenobiotics 20%
• Prostaglandins 17%
• Pharmaceutical Preparations 15%
• Steroids 13%
• Oxidative Stress 13%
• Down-Regulation 13%
• Lymphocytes 12%
• Messenger RNA 10%
• Enzymes 10%
• Therapeutics 3%

Chemical Compounds

• Hemin 91%
• Cytochrome P450 79%
• Pharmacological Metabolism 57%
• Midazolam 55%
• Xenobiotic Agent 43%
• Prostaglandin 42%
• Drug 39%
• Oxidative Stress 36%
• Steroid 34%
• Metabolic 30%
• Dose 28%
• Probe 22%
• Time 13%