Changing trends in the treatment of dry-eye disease

Murat Dogru, Masatsugu Nakamura, Jun Shimazaki, Kazuo Tsubota

研究成果: Review article査読

37 被引用数 (Scopus)

抄録

Introduction: Dry eye is a visually disabling disease encountered in many countries with a wide variation of treatment practices all over the world. On that front, the 2007 Report of the International Dry Eye WorkShop (DEWS) reviewed the current knowledge on all aspects of dry-eye disease (DED), in an evidence-based manner, and outlined the trends and recommendations in the treatment of DED on the basis of disease severity. Areas covered: This review mainly focuses on treatments for DED based on severity as recommended in the DEWS report, particularly artificial eye drops, hyaluronate sodium eye drops, autologous serum, anti-inflammatory eye drops including cyclosporine and steroids, and mucin secretagogues. New dry-eye treatment modalities in current trials outlined on the clinicaltrial.gov site are also outlined. Expert opinion: Further investigations into the mechanism of action of the new mucin and tear secretagogues which have been suggested to have anti-inflammatory properties will enrich our understanding in relation to relevant ocular surface responses after treatment with these new agents.

本文言語English
ページ(範囲)1581-1601
ページ数21
ジャーナルExpert Opinion on Investigational Drugs
22
12
DOI
出版ステータスPublished - 2013 12 1

ASJC Scopus subject areas

  • 薬理学
  • 薬理学(医学)

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