TY - JOUR
T1 - Characterization of Polysaccharides Having Activity on the Reticuloendothelial System from the Rhizome of Curcuma longa
AU - Gonda, Ryoko
AU - Tomoda, Masashi
AU - Shimizu, Noriko
AU - Kanari, Mieko
PY - 1990
Y1 - 1990
N2 - Three polysaccharides, named ukonan A, ukonan B and ukonan C, were isolated from the rhizomes of Curcuma longa L. They were homogeneous on electrophoresis and gel chromatography, and showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test. They are composed of L-arabinose: D-xylose: D-galactose: D-glucose: L-rhamnose: D-galacturonic acid in the molar ratios of 12:4:12:1:4:10 (ukonan A), 12:4:12:1:2:4 (ukonan B) and 8:3:6:14:2:3 (ukonan C), in addition to small amounts of peptide moiety. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated the structural features of ukonan B, the major one in terms of the activity. It has acidic arabino-galactan type structural units.
AB - Three polysaccharides, named ukonan A, ukonan B and ukonan C, were isolated from the rhizomes of Curcuma longa L. They were homogeneous on electrophoresis and gel chromatography, and showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test. They are composed of L-arabinose: D-xylose: D-galactose: D-glucose: L-rhamnose: D-galacturonic acid in the molar ratios of 12:4:12:1:4:10 (ukonan A), 12:4:12:1:2:4 (ukonan B) and 8:3:6:14:2:3 (ukonan C), in addition to small amounts of peptide moiety. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated the structural features of ukonan B, the major one in terms of the activity. It has acidic arabino-galactan type structural units.
KW - Curcuma longa
KW - acidic arabinogalactan
KW - immunological activity
KW - methylation analysis
KW - polysaccharide structure
KW - reticuloendothelial system
KW - rhizome
KW - turmeric
KW - ukonan B
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U2 - 10.1248/cpb.38.482
DO - 10.1248/cpb.38.482
M3 - Article
C2 - 2337962
AN - SCOPUS:0025342371
SN - 0009-2363
VL - 38
SP - 482
EP - 486
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
IS - 2
ER -