抄録
SELEX is a conventional method to obtain high affinity nucleic acids to target molecules. In this study, high affinity RNA molecules against SRP19 protein were selected by using a randomized library. The primary and predicted secondary structures of the aptamers are different from those of S-domain RNA which is the natural target of SRP19 protein. Comparison of structural features between S-domain RNA and aptamers might enhance our understanding on RNA-protein interaction.
本文言語 | English |
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ページ(範囲) | 265-266 |
ページ数 | 2 |
ジャーナル | Nucleic acids symposium series (2004) |
号 | 53 |
DOI | |
出版ステータス | Published - 2009 |
外部発表 | はい |
ASJC Scopus subject areas
- 医学(全般)