Chemistry Based Approach for Degradation of Target-Oligosaccharides Using Photo-Activatable Organic Small Molecules

Daisuke Takahashi, Kazunobu Toshima

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Molecular design, chemical synthesis, and biological evaluation of several organic small molecules, which can target-selectively photodegrade oligosaccharides by irradiation with a specific wavelength of light under mild conditions without any additives, are introduced. These novel class of photochemical agents promise bright prospects for finding not only molecular-targeted bioprobes for understanding of the structure-activity relationships of oligosaccharides but also novel therapeutic drugs targeting biologically active oligosaccharides.

本文言語English
ページ(範囲)258-276
ページ数19
ジャーナルTrends in Glycoscience and Glycotechnology
24
140
DOI
出版ステータスPublished - 2012

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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