Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) after treatment for Hodgkin’s lymphoma

Kyoko Mashima, Shigeaki Suzuki, Takehiko Mori, Toshihiko Shimizu, Satoshi Yamada, Shigemichi Hirose, Shinichiro Okamoto, Norihiro Suzuki

研究成果: Article査読

13 被引用数 (Scopus)

抄録

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a rare central nervous system (CNS) disorder with distinct radiological features. However, CLIPEERS may mimic CNS lymphoma, and several cases in which CLIPPERS occurred premonitory to CNS lymphoma have been reported. We report a 31-year-old man presenting with progressive gait ataxia and the characteristic MRI features of CLIPPERS. He was diagnosed with stage II Hodgkin’s lymphoma at the age of 15, and we considered the possibility of newly emerged CNS lymphoma occurring in the immunosuppressive condition after the treatment of Hodgkin’s lymphoma. Histological findings showed no evidence of CNS lymphoma and the neurological symptoms were resolved by steroids. Although CLIPPERS developed in the reverse order in this case, CLIPPERS should be considered in different diagnosis for CNS lymphoma.

本文言語English
ページ(範囲)709-712
ページ数4
ジャーナルInternational Journal of Hematology
102
6
DOI
出版ステータスPublished - 2015 12 1

ASJC Scopus subject areas

  • Hematology

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