Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome

K. Michizono, F. Umehara, T. Hashiguchi, K. Arimura, E. Matsuura, O. Watanabe, N. Fujimoto, Y. Okada, M. Osame

研究成果: Article

22 引用 (Scopus)

抄録

The authors quantitatively measured levels of matrix metalloproteinases (MMP), tissue inhibitor of metalloproteinases (TIMP), and vascular endothelial growth factor (VEGF) in blood samples of POEMS syndrome. Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 were more increased in patients with POEMS syndrome than in patients with other neurologic disorders or in healthy controls. Serum levels of VEGF and TIMP-1 were strongly correlated with each other. Increased circulating levels of MMP-1, -2, -3, -9, and TIMP-1 may lead to a better understanding the pathogenesis of POEMS syndrome.

元の言語English
ページ(範囲)807-810
ページ数4
ジャーナルNeurology
56
発行部数6
出版物ステータスPublished - 2001 3 27

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POEMS Syndrome
Matrix Metalloproteinase 1
Tissue Inhibitor of Metalloproteinase-1
Matrix Metalloproteinase 2
Vascular Endothelial Growth Factor A
Tissue Inhibitor of Metalloproteinases
Matrix Metalloproteinase Inhibitors
Nervous System Diseases
Serum

ASJC Scopus subject areas

  • Neuroscience(all)

これを引用

Michizono, K., Umehara, F., Hashiguchi, T., Arimura, K., Matsuura, E., Watanabe, O., ... Osame, M. (2001). Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome. Neurology, 56(6), 807-810.

Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome. / Michizono, K.; Umehara, F.; Hashiguchi, T.; Arimura, K.; Matsuura, E.; Watanabe, O.; Fujimoto, N.; Okada, Y.; Osame, M.

:: Neurology, 巻 56, 番号 6, 27.03.2001, p. 807-810.

研究成果: Article

Michizono, K, Umehara, F, Hashiguchi, T, Arimura, K, Matsuura, E, Watanabe, O, Fujimoto, N, Okada, Y & Osame, M 2001, 'Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome', Neurology, 巻. 56, 番号 6, pp. 807-810.
Michizono K, Umehara F, Hashiguchi T, Arimura K, Matsuura E, Watanabe O その他. Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome. Neurology. 2001 3 27;56(6):807-810.
Michizono, K. ; Umehara, F. ; Hashiguchi, T. ; Arimura, K. ; Matsuura, E. ; Watanabe, O. ; Fujimoto, N. ; Okada, Y. ; Osame, M. / Circulating levels of MMP-1, -2, -3, -9, and TIMP-1 are increased in POEMS syndrome. :: Neurology. 2001 ; 巻 56, 番号 6. pp. 807-810.
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AU - Arimura, K.

AU - Matsuura, E.

AU - Watanabe, O.

AU - Fujimoto, N.

AU - Okada, Y.

AU - Osame, M.

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