Clinical, microbiological, and immunological studies following initial preparation in adult periodontitis.

Taneaki Nakagawa, S. Yamada, M. Tsunoda, T. Sato, Y. Naito, I. Takazoe, K. Okuda

研究成果: Article

14 引用 (Scopus)

抄録

This study investigated the clinical, microbiological and immunological changes induced in adult periodontitis by initial preparation. Microflora in periodontal lesions was mainly examined by cultural methods, and serum IgG antibody levels were measured by an enzyme linked immunosorbent assay. Black-pigmented gram negative anaerobes, especially Porphyromonas (Bacteroides) gingivalis, was predominant in periodontal pockets with adult destructive periodontitis. Significantly elevated serum IgG antibody levels to P. gingivalis was found in high frequency, and these serum IgG antibody levels correlated with the presence of P. gingivalis in periodontal pockets, not with other bacteria tested. Total-CFU was significantly reduced and clinical conditions were improved after supragingival plaque control, but the microflora themselves showed few changes. Although reduction of total-CFU and changes in microflora were observed following scaling and root planing, it was found to be difficult to completely eliminate periodontopathic bacteria from periodontal pockets. Although serum IgG antibody levels to P. gingivalis was significantly reduced following initial preparation, the levels were still elevated from those of the controls. It was found that the presence of P. gingivalis was correlated with clinical conditions, including bleeding on probing and residual pocket depth following initial preparation.

元の言語English
ページ(範囲)321-331
ページ数11
ジャーナルThe Bulletin of Tokyo Dental College
31
発行部数4
出版物ステータスPublished - 1990 11
外部発表Yes

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Chronic Periodontitis
Periodontal Pocket
Immunoglobulin G
Porphyromonas gingivalis
Antibodies
Serum
Root Planing
Bacteria
Enzyme-Linked Immunosorbent Assay
Hemorrhage

ASJC Scopus subject areas

  • Medicine(all)

これを引用

Clinical, microbiological, and immunological studies following initial preparation in adult periodontitis. / Nakagawa, Taneaki; Yamada, S.; Tsunoda, M.; Sato, T.; Naito, Y.; Takazoe, I.; Okuda, K.

:: The Bulletin of Tokyo Dental College, 巻 31, 番号 4, 11.1990, p. 321-331.

研究成果: Article

Nakagawa, T, Yamada, S, Tsunoda, M, Sato, T, Naito, Y, Takazoe, I & Okuda, K 1990, 'Clinical, microbiological, and immunological studies following initial preparation in adult periodontitis.', The Bulletin of Tokyo Dental College, 巻. 31, 番号 4, pp. 321-331.
Nakagawa, Taneaki ; Yamada, S. ; Tsunoda, M. ; Sato, T. ; Naito, Y. ; Takazoe, I. ; Okuda, K. / Clinical, microbiological, and immunological studies following initial preparation in adult periodontitis. :: The Bulletin of Tokyo Dental College. 1990 ; 巻 31, 番号 4. pp. 321-331.
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