Clinical outcome in patients with small intestinal non-Hodgkin lymphoma

Shinichi Kako, Kumi Oshima, Miki Sato, Kiriko Terasako, Shinya Okuda, Hideki Nakasone, Rie Yamazaki, Yukie Tanaka, Aki Tanihara, Yutaka Kawamura, Hirokazu Kiyosaki, Takakazu Higuchi, Junji Nishida, Fumio Konishi, Yoshinobu Kanda

研究成果: Article

18 引用 (Scopus)

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The clinical features and outcome of small intestinal lymphoma remain unclear. We retrospectively analyzed 23 patients who had non-Hodgkin lymphoma with a small intestinal lesion. With a median follow-up of 37 months, the 5-year overall survival and failure-free survival (FFS) were 64% and 60%, respectively. In a univariate analysis, a worse performance status at the start of treatment and the occurrence of abdominal symptoms or perforation during treatment were associated with poor survival. Perforation often resulted in a dismal prognosis in patients with uncontrollable lymphoma, but not in patients with lymphoma in remission. The role of surgery in small intestinal lymphoma remains equivocal. In the current study, surgery before other therapies favorably influenced FFS, and all patients who underwent complete resection of the small intestinal lesion had extremely favorable results. Further studies are warranted to establish optimal therapeutic strategies.

元の言語English
ページ(範囲)1618-1624
ページ数7
ジャーナルLeukemia and Lymphoma
50
発行部数10
DOI
出版物ステータスPublished - 2009 11 11
外部発表Yes

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ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

これを引用

Kako, S., Oshima, K., Sato, M., Terasako, K., Okuda, S., Nakasone, H., Yamazaki, R., Tanaka, Y., Tanihara, A., Kawamura, Y., Kiyosaki, H., Higuchi, T., Nishida, J., Konishi, F., & Kanda, Y. (2009). Clinical outcome in patients with small intestinal non-Hodgkin lymphoma. Leukemia and Lymphoma, 50(10), 1618-1624. https://doi.org/10.1080/10428190903147629