Coexistence of CREST syndrome and primary biliary cirrhosis. Serological studies of two cases

M. Hirakata, M. Akizuki, K. Miyachi, H. Matsushima, T. Okano, M. Homma

研究成果: Article査読

15 被引用数 (Scopus)

抄録

Two patients with characteristic features of CREST syndrome and primary biliary cirrhosis are reported. Sera of both patients contained autoantibodies to centromere and mitochondrial antigens. Immunodiffusion analysis identified the specificities of precipitating antibodies of mitochondria of the first case as anti-M-A and M-C, and of the second case as anti-M-A and M-B antibodies. Simultaneous occurrence of 2 marker antibodies in an individual patient indicates that the 2 patients reported here have CREST syndrome and primary biliary cirrhosis, both of which are considered as a distinct clinical entity.

本文言語English
ページ(範囲)1166-1170
ページ数5
ジャーナルJournal of Rheumatology
15
7
出版ステータスPublished - 1988 1 1

ASJC Scopus subject areas

  • リウマチ学
  • 免疫アレルギー学
  • 免疫学

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