TY - JOUR
T1 - Comparison of DNA polymerase between Entamoeba histolytica and E. dispar
AU - Makioka, Asao
AU - Ohtomo, Hiroshi
AU - Kobayashi, Seiki
AU - Takeuchi, Tsutomu
PY - 1997/3
Y1 - 1997/3
N2 - We have previously reported DNA polymerase activity of Entamoeba histolytica. The present study was aimed to compare the activity of E. histolytica with that of E. dispar, which formerly was known as the non-pathogenic strain of E. histolytica. The level of activity of E. dispar was comparable to that of E. histolytica. Also, dependence of the activities of both species on pH, salt, Mg2+, and sensitivity to inhibitors of mammalian DNA polymerases were almost the same. Thus the E. dispar enzyme was very similar to the E. histolytica enzyme quantitatively and qualitatively.
AB - We have previously reported DNA polymerase activity of Entamoeba histolytica. The present study was aimed to compare the activity of E. histolytica with that of E. dispar, which formerly was known as the non-pathogenic strain of E. histolytica. The level of activity of E. dispar was comparable to that of E. histolytica. Also, dependence of the activities of both species on pH, salt, Mg2+, and sensitivity to inhibitors of mammalian DNA polymerases were almost the same. Thus the E. dispar enzyme was very similar to the E. histolytica enzyme quantitatively and qualitatively.
KW - DNA polymerase activity
KW - E. dispar
KW - Entamoeba histolytica
UR - http://www.scopus.com/inward/record.url?scp=0042732878&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0042732878&partnerID=8YFLogxK
U2 - 10.1016/S1383-5769(97)00005-6
DO - 10.1016/S1383-5769(97)00005-6
M3 - Article
AN - SCOPUS:0042732878
SN - 1383-5769
VL - 46
SP - 27
EP - 30
JO - Parasitology International
JF - Parasitology International
IS - 1
ER -
