Comparison of temporal response to cerebral blood flow measured by laser speckle flowgraphy and laser doppler flowmetry

Masashi Kusano, Haruka Nakayama, Hiroyuki Takuwa, Kazuto Masamoto, Iwao Kanno, Eiji Okada

研究成果: Conference contribution

抜粋

Cerebral blood flow (CBF) change of mice during whisker stimulation is measured by laser speckle flowgraphy (LSFG) and laser Doppler flowmetry (LDF). Laser speckle flowgraphy (LSFG) has been used to obtain the two-dimensional distribution of the blood flow in tissue as well as scanning laser Doppler flowmetry (LDF). There are several parameters of LSFG to obtain the blood flow maps and the distribution change of blood flow. In this study, we calculate four parameters from the speckle pattern to measure CBF in awake mice. The temporal resolution of LSFG is likely to be less than that of LDF. The temporal changes in CBF obtained from the four parameters calculated from the speckle pattern detected by a common CCD camera are compared with those measured by LDF. The time courses of CBF change measured by LSFG highly correlate with those by LDF. The results indicate that the temporal response of LSFG is sufficient to measure CBF change evoked by brain activations.

元の言語English
ホスト出版物のタイトルEuropean Conference on Biomedical Optics, ECBO 2011
出版者Optical Society of America (OSA)
ISBN(印刷物)9780819486837
DOI
出版物ステータスPublished - 2011 1 1
イベントEuropean Conference on Biomedical Optics, ECBO 2011 - Munich, Germany
継続期間: 2011 5 222011 5 26

出版物シリーズ

名前Optics InfoBase Conference Papers
ISSN(電子版)2162-2701

Other

OtherEuropean Conference on Biomedical Optics, ECBO 2011
Germany
Munich
期間11/5/2211/5/26

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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  • これを引用

    Kusano, M., Nakayama, H., Takuwa, H., Masamoto, K., Kanno, I., & Okada, E. (2011). Comparison of temporal response to cerebral blood flow measured by laser speckle flowgraphy and laser doppler flowmetry. : European Conference on Biomedical Optics, ECBO 2011 [80880E] (Optics InfoBase Conference Papers). Optical Society of America (OSA). https://doi.org/10.1364/ecbo.2011.80880e