Concordance in judgment of clinical borders of basal cell carcinomas in Japanese patients: A preliminary study of JCOG2005 (J-BASE-MARGIN)

Anna Kamimura, Yasuhiro Nakamura, Tatsuya Takenouchi, Shigeto Matsushita, Toshikazu Omodaka, Kentaro Yamamura, Hiroshi Uchi, Shusuke Yoshikawa, Hiroto Yanagisawa, Takamichi Ito, Yoshio Kiyohara, Yoshio Nakamura, Megumi Aoki, Shoichiro Ishizuki, Kohei Oashi, Takuya Miyagawa, Taku Maeda, Dai Ogata, Naohito Hatta, Shuichi OheTaiki Isei, Akira Takahashi, Yoshiyasu Umeda, Buntaro Yamaguchi, Masashi Ishikawa, Kohei Horimoto, Yasuhiro Fujsawa, Jiro Uehara, Yoshitsugu Shibayama, Yukiko Kiniwa, Yu Kawahara, Taisuke Matsuya, Hisashi Uhara, Junji Kato, Yoshiyuki Nakamura, Takuo Murakami, Kenjiro Namikawa, Koji Yoshino, Takeru Funakoshi, Sumiko Takatsuka, Yu Matsui, Jin Sasaki, Hiroshi Koga, Kenji Yokota, Takaya Komori, Satoshi Fukushima, Naoya Yamazaki

研究成果: Article査読

抄録

Basal cell carcinoma is the most common type of skin cancer, and surgical excision with clear margins is the standard of care. Surgical margins are determined based on risk factors (high or low risk) for recurrence according to the National Comprehensive Cancer Network and Japanese basal cell carcinoma guidelines. The clarity of the clinical tumor border (well-defined or poorly defined) is considered a risk factor, and significant discrepancies in the judgment of clinical tumor borders among dermato-oncologists may occur. Therefore, we analyzed the dermato-oncologists’ concordance in judging the clinical tumor border of basal cell carcinoma. Forty-seven dermato-oncologists (experts: 37; young trainees: 10) participated in this study. The datasets of clinical and dermoscopic photographs of 79 Japanese cases of head and neck basal cell carcinoma were used to determine the concordance in the judgment of clinical tumor border. The probability of the border that was selected more often was used to calculate the rater agreement rate for each dataset. Correct judgment was defined as a more frequently selected border, and the concordance rate of clarity of clinical tumor border for each dermato-oncologist was calculated based on the definition of the correct judgment. A median concordance rate of 85% or higher for all dermato-oncologists was predefined as an acceptable rate for clinical use. Of the 79 datasets, rater agreement rates were 80–100%, 60–79%, and 51–59% for 55, 19, and five datasets, respectively. The median concordance rate for all dermato-oncologists was 86% (interquartile range: 82–89%). There was no significant difference in the concordance rate between the experts and the trainees (median, 87% vs. 85.5%; p = 0.58). The concordance rates of dermato-oncologists for all datasets were relatively high and acceptable for clinical use.

本文言語English
ページ(範囲)837-844
ページ数8
ジャーナルJournal of Dermatology
49
9
DOI
出版ステータスPublished - 2022 9月

ASJC Scopus subject areas

  • 皮膚病学

フィンガープリント

「Concordance in judgment of clinical borders of basal cell carcinomas in Japanese patients: A preliminary study of JCOG2005 (J-BASE-MARGIN)」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル