Congenital bronchial atresia in infants and children

Nobuyuki Morikawa, Tatsuo Kuroda, Toshiro Honna, Yoshihiro Kitano, Yasushi Fuchimoto, Kan Terawaki, Kazuteru Kawasaki, Goro Koinuma, Kentaro Matsuoka, Morihiro Saeki

研究成果: Article査読

37 被引用数 (Scopus)

抄録

Background/Purpose: Congenital bronchial atresia (CBA) usually presents incidentally in asymptomatic young male adults but is rarely diagnosed in children. The aim of this study was to clarify the clinical characteristics of CBA in childhood and to describe the spectrum of this condition. Methods: The clinical features in 29 patients with CBA, aged from 1 day to 13 years (median, 4 years), were reviewed retrospectively. Diagnosis was confirmed by pathological findings of a blind-ending bronchus associated with distal mucous-filled bronchocele surrounded by hyperinflated lung parenchyma. Results: All but 1 patient were symptomatic. The most frequent symptom was productive cough and fever owing to recurrent pneumonia found in 26 children. Two infants suffered from respiratory distress. Chest x-ray showed various findings of infiltrative pneumonia, emphysema, and a large cyst. Computed tomography, bronchography, and bronchoscopy were useful modalities for demonstrating bronchocele associated with hyperinflated lung or proximal blind-ending bronchus even in infected cases. The right lower lobe was predominantly affected in 12 cases, followed by left or right upper lobe in 7 cases. Lobectomy or segmentectomy resulted in remarkable clinical improvement. Conclusions: Congenital bronchial atresia presents differently in children than in young adults. Modern imaging techniques and careful pathological analyses lead to an accurate diagnosis of bronchial atresia, which may be misdiagnosed as intralobar sequestration or pulmonary bronchial cysts. Bronchial atresia is a distinct pathological entity that accounts for recurrent pneumonia or respiratory distress in childhood, requiring surgical treatment.

本文言語English
ページ(範囲)1822-1826
ページ数5
ジャーナルJournal of Pediatric Surgery
40
12
DOI
出版ステータスPublished - 2005 12
外部発表はい

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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