Connectable DNA-logic operation using droplets and rupture/reformation of bilayer lipid membranes

K. Inoue, R. Kawano, H. Yasuga, M. Takinoue, T. Osaki, K. Kamiya, N. Miki, S. Takeuchi

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

This paper experimentally demonstrated the connection of logic gates using DNA and membrane protein's channel reconstituted into bilayer lipid membranes (BLMs). In this system, droplets worked as the carrier of DNA to convey it as biological signal to next stage and reformation and rupture of BLM accelerated DNA transfer between droplets. Furthermore, DNA is detected based on the electrical and physical characters of DNA translocation via membrane protein's channel. In this study, we successfully demonstrated NOR operation by connecting OR and NOT gate. This system is readily applicable to develop high sensitive biosensor and computing system imitating biological information processing.

本文言語English
ホスト出版物のタイトル2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
出版社Institute of Electrical and Electronics Engineers Inc.
ページ739-742
ページ数4
ISBN(電子版)9781479989553
DOI
出版ステータスPublished - 2015 8 5
イベント18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 - Anchorage, United States
継続期間: 2015 6 212015 6 25

出版物シリーズ

名前2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015

Other

Other18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
国/地域United States
CityAnchorage
Period15/6/2115/6/25

ASJC Scopus subject areas

  • 器械工学
  • 電子工学および電気工学

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