Construction of stable capillary networks using a microfluidic device

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

Construction of stable capillary networks is required to provide sufficient oxygen and nutrients to the deep region of thick tissues, which is important in the context of 3D tissue engineering. Although conventional in vitro culture models have been used to investigate the mechanism of capillary formation, recent advances in microfluidics technologies allowed us to control biophysical and biochemical culture environments more precisely, which led to the construction of functional and stable capillary networks. In this study, endothelial cells and mesenchymal stem cells were co-cultured in microfluidic devices to construct stable capillary networks, which resulted in the construction of luminal structures covered by pericytes. Interactions between endothelial cells and mesenchymal stem cells are also discussed in the context of capillary formation.

本文言語English
ホスト出版物のタイトルProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
出版社Institute of Electrical and Electronics Engineers Inc.
ページ350-353
ページ数4
2015-November
ISBN(印刷版)9781424492718
DOI
出版ステータスPublished - 2015 11 4
イベント37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
継続期間: 2015 8 252015 8 29

Other

Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
国/地域Italy
CityMilan
Period15/8/2515/8/29

ASJC Scopus subject areas

  • コンピュータ ビジョンおよびパターン認識
  • 信号処理
  • 生体医工学
  • 健康情報学

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