Construction of the inbred strain

研究成果: Chapter

2 被引用数 (Scopus)

抄録

Genetically homogeneous populations such as inbred strains are valuable experimental tools in various fields of biomedical analyses. In many animals, inbred strains are established by consecutive sib-pair mating for a minimum of 20 generations. As the generation proceeds, fitness of the population reduces usually. Therefore, in order to establish inbred strains, the important point is the selection of pairs in good condition at each generation. Here, I describe the procedure and tips for generating inbred strains in zebrafish.

本文言語English
ホスト出版物のタイトルMethods in Molecular Biology
出版社Humana Press Inc.
ページ107-118
ページ数12
1451
DOI
出版ステータスPublished - 2016

出版物シリーズ

名前Methods in Molecular Biology
1451
ISSN(印刷版)10643745

ASJC Scopus subject areas

  • 医学(全般)
  • 分子生物学
  • 遺伝学

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