Continuous glucose monitoring in an infant with panhypopituitarism having hypoglycemia on growth hormone therapy

Kaho Kiuchi, Takeshi Sato, Satsuki Nakano, Tomohiro Ishii, Tomonobu Hasegawa

研究成果: Article査読

抄録

Objectives: The usefulness of continuous glucose monitoring (CGM) in infants with panhypopituitarism (PH) having hypoglycemia is yet to be explored. The potential adverse effects of growth hormone (GH) replacement therapy, such as hyperglycemia, cannot be comprehensively evaluated using the conventional measurement. Case presentation: A 2-month-old infant with PH, including severe GH deficiency, had hypoglycemia despite frequent feeding. Glucose levels were monitored using CGM before and after GH replacement therapy. The proportion of time for hypoglycemia decreased from 4.9 to 0% (p<0.017). Hyperglycemia did not increase. The CGM method did not contribute to any adverse events requiring intervention. Our patient only experienced minor bleeding and no episode of cellulitis. Conclusions: CGM is useful in controlling glucose levels in infants with hypoglycemia and PH.

本文言語English
ページ(範囲)1556-1559
ページ数4
ジャーナルJournal of Pediatric Endocrinology and Metabolism
35
12
DOI
出版ステータスPublished - 2022 12月 1

ASJC Scopus subject areas

  • 小児科学、周産期医学および子どもの健康
  • 内分泌学、糖尿病および代謝内科学
  • 内分泌学

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