Convergent total synthesis of epolactaene: Application of bridgehead oxiranyl anion strategy

Kouji Kuramochi, Seigo Nagata, Hideyoshi Itaya, Kenichi Takao, Susumu Kobayashi

研究成果: Article

34 引用 (Scopus)

抄録

Total synthesis of (+)-epolactaene was accomplished by a convergent approach utilizing the fluoride anion-catalyzed aldol-type reaction of (-)-α-trimethylsilylangelica lactone epoxide with tetraene aldehyde as a key reaction.

元の言語English
ページ(範囲)7371-7374
ページ数4
ジャーナルTetrahedron Letters
40
発行部数41
DOI
出版物ステータスPublished - 1999 10 8
外部発表Yes

Fingerprint

Epoxy Compounds
Lactones
Fluorides
Aldehydes
Anions
epolactaene
3-hydroxybutanal

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

これを引用

Convergent total synthesis of epolactaene : Application of bridgehead oxiranyl anion strategy. / Kuramochi, Kouji; Nagata, Seigo; Itaya, Hideyoshi; Takao, Kenichi; Kobayashi, Susumu.

:: Tetrahedron Letters, 巻 40, 番号 41, 08.10.1999, p. 7371-7374.

研究成果: Article

Kuramochi, Kouji ; Nagata, Seigo ; Itaya, Hideyoshi ; Takao, Kenichi ; Kobayashi, Susumu. / Convergent total synthesis of epolactaene : Application of bridgehead oxiranyl anion strategy. :: Tetrahedron Letters. 1999 ; 巻 40, 番号 41. pp. 7371-7374.
@article{09ab221169224718a5dd7a731d4e0eb6,
title = "Convergent total synthesis of epolactaene: Application of bridgehead oxiranyl anion strategy",
abstract = "Total synthesis of (+)-epolactaene was accomplished by a convergent approach utilizing the fluoride anion-catalyzed aldol-type reaction of (-)-α-trimethylsilylangelica lactone epoxide with tetraene aldehyde as a key reaction.",
keywords = "β-Angelica lactone epoxide, Epolactaene, Fluoride-catalyzed aldol reaction, Oxiranyl anion",
author = "Kouji Kuramochi and Seigo Nagata and Hideyoshi Itaya and Kenichi Takao and Susumu Kobayashi",
year = "1999",
month = "10",
day = "8",
doi = "10.1016/S0040-4039(99)01512-9",
language = "English",
volume = "40",
pages = "7371--7374",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "41",

}

TY - JOUR

T1 - Convergent total synthesis of epolactaene

T2 - Application of bridgehead oxiranyl anion strategy

AU - Kuramochi, Kouji

AU - Nagata, Seigo

AU - Itaya, Hideyoshi

AU - Takao, Kenichi

AU - Kobayashi, Susumu

PY - 1999/10/8

Y1 - 1999/10/8

N2 - Total synthesis of (+)-epolactaene was accomplished by a convergent approach utilizing the fluoride anion-catalyzed aldol-type reaction of (-)-α-trimethylsilylangelica lactone epoxide with tetraene aldehyde as a key reaction.

AB - Total synthesis of (+)-epolactaene was accomplished by a convergent approach utilizing the fluoride anion-catalyzed aldol-type reaction of (-)-α-trimethylsilylangelica lactone epoxide with tetraene aldehyde as a key reaction.

KW - β-Angelica lactone epoxide

KW - Epolactaene

KW - Fluoride-catalyzed aldol reaction

KW - Oxiranyl anion

UR - http://www.scopus.com/inward/record.url?scp=0033536723&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033536723&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(99)01512-9

DO - 10.1016/S0040-4039(99)01512-9

M3 - Article

AN - SCOPUS:0033536723

VL - 40

SP - 7371

EP - 7374

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 41

ER -