Creation of a cell-based separation microdevice using human renal proximal tubule epithelial cells

Xiaofang Gao, Kazuma Mawatari, Yutaka Kazoe, Yo Tanaka, Takehiko Kitamori

研究成果: Conference contribution

抄録

Here we report a cell-based separation microdevice using human renal proximal tubule epithelial cells. Near organ-level of separation efficiency and selectivity including reabsorption and clearance by renal tubule cells was demonstrated on chip. In addition, cell performance was directly measured under different operating parameters (flow rate and feeding concentration) in order to optimize the cell separating capability. This cell-base separation microdevice also referred to as bioartificial renal tubule on chip has the potential for drug screening and portable medical care device for kidney failure [1].

本文言語English
ホスト出版物のタイトルProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
出版社Chemical and Biological Microsystems Society
ページ602-604
ページ数3
ISBN(印刷版)9780979806452
出版ステータスPublished - 2012 1 1
外部発表はい
イベント16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
継続期間: 2012 10 282012 11 1

出版物シリーズ

名前Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period12/10/2812/11/1

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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