TY - JOUR
T1 - Cutaneous T‐cell lymphoma with massive co‐infiltration of polyclonal B cells
AU - YAGI, H.
AU - OGAI, M.
AU - IZUMI, T.
AU - EBIHARA, T.
AU - SUGIURA, M.
AU - TOKURA, Y.
AU - TAKIGAWA, M.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1994/2
Y1 - 1994/2
N2 - Summary A 76‐year‐old man presented with a 3‐month history of a cutaneous nodute on the right thigh. The tumour was composed of CD3+, large atypical cells, and CD20+, small normal‐appearing cells. Flow cytometry showed that CD20+ cells outnumbered CD3+ cells. By Southern blot hybridization analyses, the malignant cells were shown to be of T‐cell origin, because of the presence of rearranged bands for the β chain of the T‐cell receptor, but not for the immunoglobulin heavy chain. This case represents a T‐cell lymphoma intermingled with a large number of non‐neoplastic B cells.
AB - Summary A 76‐year‐old man presented with a 3‐month history of a cutaneous nodute on the right thigh. The tumour was composed of CD3+, large atypical cells, and CD20+, small normal‐appearing cells. Flow cytometry showed that CD20+ cells outnumbered CD3+ cells. By Southern blot hybridization analyses, the malignant cells were shown to be of T‐cell origin, because of the presence of rearranged bands for the β chain of the T‐cell receptor, but not for the immunoglobulin heavy chain. This case represents a T‐cell lymphoma intermingled with a large number of non‐neoplastic B cells.
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U2 - 10.1111/j.1365-2133.1994.tb02905.x
DO - 10.1111/j.1365-2133.1994.tb02905.x
M3 - Article
C2 - 7510123
AN - SCOPUS:0028242019
VL - 130
SP - 226
EP - 230
JO - British Journal of Dermatology
JF - British Journal of Dermatology
SN - 0007-0963
IS - 2
ER -