抄録
The novel enyne-allene sulfones 5-8 were prepared by m-chloroperbenzoic acid oxidation of the corresponding enediyne sulfides 1-4; the enyne-allene sulfones 6-8 having a leaving group at the allylic position were aromatized by 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) via the allene-ene-cumulene intermediate 10 and showed DNA-cleaving activities under basic conditions without any additive.
本文言語 | English |
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ページ(範囲) | 1406-1407 |
ページ数 | 2 |
ジャーナル | Journal of the Chemical Society, Chemical Communications |
号 | 18 |
DOI | |
出版ステータス | Published - 1993 12 1 |
ASJC Scopus subject areas
- Molecular Medicine