抄録
The effect of the immunosuppressant cyclosporin A on the survivability of newborn mouse cerebral cortex transplanted into the third ventricle of adult rats was investigated. Hematoxylin staining revealed that the transplanted mouse brain tissue was rejected by 4 weeks after the transplantation in the control group. In contrast, a large mass of grafted tissue was clearly detected in the third ventricle even 4 weeks after the transplantation in the cyclosporin A-treated group, and the grafted tissue was heavily stained with Thy-1.2 mouse monoclonal antibody. The results indicate that cyclosporin A is an effective immunosuppressant in neuronal transplantation as well as in transplantation of other organs.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 85-90 |
| ページ数 | 6 |
| ジャーナル | Neuroscience Letters |
| 巻 | 54 |
| 号 | 1 |
| DOI | |
| 出版ステータス | Published - 1985 1月 1 |
ASJC Scopus subject areas
- 神経科学（全般）