Cytokines regulate c-Met expression in cultured astrocytes

Kenji Shimazaki, Kazunari Yoshida, Yuji Hirose, Hisatsugu Ishimori, Makoto Katayama, Takeshi Kawase

研究成果: Article査読

14 被引用数 (Scopus)

抄録

We investigated c-Met expression in cultured astrocytes and their regulation by cytokines. Immunocytochemistry revealed that c-Met was expressed in cultured astrocytes. Western blotting revealed that acidic and basic fibroblast growth factor (FGF) enhanced and hepatocyte growth factor (HGF) reduced c-Met expression. Reverse transcription-polymerase chain reaction revealed that FGFs and HGF enhanced c-met expression. These findings suggest that c-Met expressed in astrocytes may have important roles during the nervous system regeneration.

本文言語English
ページ(範囲)105-110
ページ数6
ジャーナルBrain Research
962
1-2
DOI
出版ステータスPublished - 2003 2月 7

ASJC Scopus subject areas

  • 神経科学(全般)
  • 分子生物学
  • 臨床神経学
  • 発生生物学

フィンガープリント

「Cytokines regulate c-Met expression in cultured astrocytes」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル