Cytologic features of oral squamous cell carcinoma in an Indo-Pacific bottlenose dolphin (Tursiops aduncus): Papanicolaou stain and immunocytochemistry using liquid-based cytology

Hiroyuki Ohsaki, Keiichi Ueda, Tomoko Minakawa, Mariko Oshiro, Shingo Kamoshida, Yuki Sugiura, Miwa Suzuki, Akira Nishiyama

研究成果: Article査読

抄録

Although oral cytology using Papanicolaou stain is useful for the early detection of oral premalignant lesions and squamous cell carcinoma (SCC) in people, little work has been conducted on this topic in veterinary medicine. This paper describes the features of oral cytology using Papanicolaou stain and immunocytochemistry on liquid-based cytology slides in a case of oral SCC in an Indo-Pacific bottlenose dolphin (Tursiops aduncus). In this case, dysplastic cells with koilocyte-like changes and SCC cells were identified using the Papanicolaou stain. These cells were positive for p53 using an immunocytochemistry analysis. A cytologic diagnosis of SCC was made. We believe that the early detection of premalignant oral lesions and SCC in dolphins can be significantly improved with cytology using liquid-based cytology, Papanicolaou staining, and immunocytochemistry.

本文言語English
ページ(範囲)404-409
ページ数6
ジャーナルVeterinary Clinical Pathology
50
3
DOI
出版ステータスPublished - 2021 9

ASJC Scopus subject areas

  • 獣医学(全般)

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