Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces: Structure determination

Hideaki Kakeya, Masaya Imoto, Yoshikazu Takahashil, Hiroshi Naganawa, Tomio Takeuchi, Kazuo Umezawa

研究成果: Article査読

31 被引用数 (Scopus)

抄録

Dephostatin, a novel tyrosine phosphatase inhibitor, was isolated from the culture broth of Streptomyces sp. MJ742-NF5. The structure was elucidated to be 2-(N-methyl-N-nitroso)hydroquinone by spectral and chemical analyses of dephostatin and its derivatives.

本文言語English
ページ(範囲)1716-1719
ページ数4
ジャーナルJournal of Antibiotics
46
11
DOI
出版ステータスPublished - 1993 7

ASJC Scopus subject areas

  • 薬理学
  • 創薬

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