Derivatives of Dictyostelium differentiation-inducing factors suppress the growth of Plasmodium parasites in vitro and in vivo

Medicine & Life Sciences

• 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone 82%
• Dictyostelium 62%
• Plasmodium 57%
• Parasites 40%
• Growth 24%
• In Vitro Techniques 21%
• artemisinine 20%
• Dictyosteliida 13%
• Plasmodium berghei 10%
• Chloroquine 9%
• Antimalarials 8%
• Plasmodium falciparum 8%
• Malaria 7%
• Lead 7%
• Rodentia 6%
• Public Health 5%
• Animals 4%
• Pharmaceutical Preparations 3%
• Therapeutics 2%

Chemical Compounds

• Differentiation-Inducing Factor 100%
• Strain 22%
• Chloroquine 10%
• Intraperitoneal 10%
• Antimalarial Agent 10%
• Dose 6%
• Bioactivity 5%
• Resistance 5%
• Drug 4%