Design and synthesis of calcium and magnesium ionophores based on double-armed diazacrown ether compounds and their application to an ion-sensing component for an ion-selective electrode

Koji Suzuki, Kazuhiko Watanabe, Yukihiro Matsumoto, Mitsuru Kobayashi, Sayaka Sato, Dwi Siswanta, Hideaki Hisamoto

研究成果: Article

92 引用 (Scopus)

抄録

The double-armed diazacrown ethers, which have a base diazacrown ether ring with two diamide-type side chains, were designed and synthesized on the basis of the proposed molecular model for the novel neutral Ca2+ and Mg2+ ionophores. The potentiometric ion-selective electrodes were prepared with over 20 kinds of systematically synthesized diazacrown ether derivatives. The relationship between the molecular structures of the ionophores and the ion selectivities was fully discussed. The electrodes based on the 21- and 18-membered diazacrown ether derivatives possessing a glycolic diamide and malonic diamide in their side chains (K23E1 and K22B5) exhibited excellent Ca2+ and Mg2+ selectivities, respectively. The ion-selectivity features of the novel Ca2+ and Mg2+ ionophores supply important structural information about the design of host molecules for alkaline earth metal cations.

元の言語English
ページ(範囲)324-334
ページ数11
ジャーナルAnalytical Chemistry
67
発行部数2
DOI
出版物ステータスPublished - 1995

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Diamide
Ionophores
Ether
Magnesium
Ions
Calcium
Alkaline Earth Metals
Derivatives
Ethers
Molecular structure
Cations
Electrodes
Molecules
Ion-Selective Electrodes

ASJC Scopus subject areas

  • Analytical Chemistry

これを引用

Design and synthesis of calcium and magnesium ionophores based on double-armed diazacrown ether compounds and their application to an ion-sensing component for an ion-selective electrode. / Suzuki, Koji; Watanabe, Kazuhiko; Matsumoto, Yukihiro; Kobayashi, Mitsuru; Sato, Sayaka; Siswanta, Dwi; Hisamoto, Hideaki.

:: Analytical Chemistry, 巻 67, 番号 2, 1995, p. 324-334.

研究成果: Article

Suzuki, Koji ; Watanabe, Kazuhiko ; Matsumoto, Yukihiro ; Kobayashi, Mitsuru ; Sato, Sayaka ; Siswanta, Dwi ; Hisamoto, Hideaki. / Design and synthesis of calcium and magnesium ionophores based on double-armed diazacrown ether compounds and their application to an ion-sensing component for an ion-selective electrode. :: Analytical Chemistry. 1995 ; 巻 67, 番号 2. pp. 324-334.
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AU - Matsumoto, Yukihiro

AU - Kobayashi, Mitsuru

AU - Sato, Sayaka

AU - Siswanta, Dwi

AU - Hisamoto, Hideaki

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