Detection of Treponema denticola in atherosclerotic lesions

K. Okuda, K. Ishihara, T. Nakagawa, A. Hirayama, Y. Inayama, K. Okuda

研究成果: Article査読

85 被引用数 (Scopus)

抄録

We examined 26 atherosclerotic lesions and 14 nondiseased aorta specimens to detect the periodontopathogenic part of the bacterial 16S rRNA locus by PCR. Treponema denticola sequence of the 16S rRNA locus was found in 6 out of 26 DNA samples (23.1%) from the formalin-fixed, paraffin-embeded atherosclerotic lesions obtained during surgery but not in any of the 14 nondiseased aorta samples from deceased persons. Utilizing immnnofluorescence microscopy, we observed aggregated antigenic particles reacting with rabbit antiserum against T. denticola in thin sections of the PCR-positive samples, but we could not detect any reacting particles in the PCR-negative thin sections.

本文言語English
ページ(範囲)1114-1117
ページ数4
ジャーナルJournal of Clinical Microbiology
39
3
DOI
出版ステータスPublished - 2001
外部発表はい

ASJC Scopus subject areas

  • Microbiology (medical)

フィンガープリント 「Detection of Treponema denticola in atherosclerotic lesions」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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