Developing and integrating an adverse drug reaction reporting system with the hospital information system.

Satoshi Kataoka, Kazuhiko Ohe, Mayumi Mochizuki, Shiro Ueda

研究成果: Article査読

6 被引用数 (Scopus)


We have developed an adverse drug reaction (ADR) reporting system integrating it with Hospital Information System (HIS) of the University of Tokyo Hospital. Since this system is designed with JAVA, it is portable without re-compiling to any operating systems on which JAVA virtual machines work. In this system, we implemented an automatic data filling function using XML-based (extended Markup Language) files generated by HIS. This new specification would decrease the time needed for physicians and pharmacists to fill the spontaneous ADR reports. By clicking a button, the report is sent to the text database through Simple Mail Transfer Protocol (SMTP) electronic mails. The destination of the report mail can be changed arbitrarily by administrators, which adds this system more flexibility for practical operation. Although we tried our best to use the SGML-based (Standard Generalized Markup Language) ICH M2 guideline to follow the global standard of the case report, we eventually adopted XML as the output report format. This is because we found some problems in handling two bytes characters with ICH guideline and XML has a lot of useful features. According to our pilot survey conducted at the University of Tokyo Hospital, many physicians answered that our idea, integrating ADR reporting system to HIS, would increase the ADR reporting numbers.

ジャーナルYakugaku zasshi : Journal of the Pharmaceutical Society of Japan
出版ステータスPublished - 2002 1月

ASJC Scopus subject areas

  • 薬理学
  • 薬科学


「Developing and integrating an adverse drug reaction reporting system with the hospital information system.」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。