Development of allergic bronchopulmonary aspergillosis in a patient with Crohn's disease

Hisashi Sasaki, Jun Miyata, Yohei Maki, Yoshifumi Kimizuka, Nobuyoshi Hayashi, Yuji Fujikura, Akihiko Kawana

研究成果: Article査読

5 被引用数 (Scopus)

抄録

Allergic bronchopulmonary aspergillosis (ABPA) is an eosinophilic inflammatory condition characterized by exaggerated immune responses to the fungal genus Aspergillus. Pulmonary manifestations in patients with Crohn's disease (CD) are frequent comorbidities. A 66-year-old man with CD treated with an anti-tumor necrosis factor-α antibody presented with dyspnea. Laboratory findings of elevated blood eosinophils and total serum IgE and positive aspergillus-specific antibodies as well as imaging findings of central bronchiectasis and mucoid impaction indicated a diagnosis of ABPA. To our knowledge, this is the first report of ABPA arising in a patient with CD. We discuss the pathophysiological mechanism of this rare complication.

本文言語English
ページ(範囲)2835-2838
ページ数4
ジャーナルInternal Medicine
58
19
DOI
出版ステータスPublished - 2019
外部発表はい

ASJC Scopus subject areas

  • 内科学

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