Development of microfluidic droplet shooter for ultrahigh-sensitive mass spectrometry

Yutaka Kazoe, Yusuke Shimizu, Yasushi Terui, Kyojiro Morikawa, Kazuma Mawatari, Takehiko Kitamori

研究成果: Conference contribution

2 被引用数 (Scopus)

抄録

Here we proposed and developed a microfluidic device to continuously shoot pL droplets toward controlled direction at kHz, and verified a novel sample injection interface with mass spectrometry (MS). Utilizing microscale laminar gas flows of 10 m/s enabled formation and shooting of uniform droplets and accurate trajectory control. On the contrary to a few percent sample injection rate by conventional electrospray ionization (ESI), the proposed microdroplet shooter can achieve 100% injection for ultrahigh sensitive MS detection. This study will open a new horizon for separation analysis, especially proteins and peptides which are important in state-of-the-art biological researches and medical diagnosis.

本文言語English
ホスト出版物のタイトル22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
出版社Chemical and Biological Microsystems Society
ページ989-990
ページ数2
ISBN(電子版)9781510897571
出版ステータスPublished - 2018
外部発表はい
イベント22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
継続期間: 2018 11 112018 11 15

出版物シリーズ

名前22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
2

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
国/地域Taiwan, Province of China
CityKaohsiung
Period18/11/1118/11/15

ASJC Scopus subject areas

  • 化学 (全般)
  • バイオエンジニアリング
  • 化学工学(その他)
  • 制御およびシステム工学

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