Development of necrotizing myopathy following interstitial lung disease with anti-signal recognition particle antibody

Tatsuya Kusumoto, Satoshi Okamori, Keita Masuzawa, Takanori Asakura, Naoshi Nishina, Shotaro Chubachi, Katsuhiko Naoki, Koichi Fukunaga, Tomoko Betsuyaku

研究成果: Article

3 引用 (Scopus)

抜粋

A 72-year-old man was admitted due to dyspnea on exertion with interstitial shadows and elevated serum creatinine kinase (CK). Despite a close examination, which included magnetic resonance imaging (MRI), we could not diagnose myopathy. Prednisolone was administered and gradually tapered. One year later, anti-signal recognition particle (SRP) antibody was confirmed and he was re-admitted for hypoxemia with elevated CK. MRI revealed muscle edema and a histopathological examination of a muscle biopsy specimen showed necrotizing myopathy. Prednisolone, cyclosporine, and intravenous immunoglobulin were administered. Physicians should carefully monitor muscle symptoms and serum CK levels in cases of interstitial lung disease with anti-SRP antibodies.

元の言語English
ページ(範囲)2045-2049
ページ数5
ジャーナルInternal Medicine
57
発行部数14
DOI
出版物ステータスPublished - 2018 1 1

ASJC Scopus subject areas

  • Internal Medicine

フィンガープリント Development of necrotizing myopathy following interstitial lung disease with anti-signal recognition particle antibody' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用