TY - JOUR
T1 - Development of the Paris definition of early Crohn's disease for disease-modification trials
T2 - Results of an international expert opinion process
AU - Peyrin-Biroulet, Laurent
AU - Billioud, Vincent
AU - D'Haens, Geert
AU - Panaccione, Remo
AU - Feagan, Brian
AU - Panés, Julian
AU - Danese, Silvio
AU - Schreiber, Stefan
AU - Ogata, Haruhiko
AU - Hibi, Toshifumi
AU - Higgins, Peter D.R.
AU - Beaugerie, Laurent
AU - Chowers, Yehuda
AU - Louis, Edouard
AU - Steinwurz, Flávio
AU - Reinisch, Walter
AU - Rutgeerts, Paul
AU - Colombel, Jean Frédéric
AU - Travis, Simon
AU - Sandborn, William J.
PY - 2012/12
Y1 - 2012/12
N2 - We report the findings and outputs of an international expert opinion process to develop a definition of early Crohn's disease (CD) that could be used in future disease-modification trials. Nineteen experts on inflammatory bowel diseases held an international expert opinion meeting to discuss and agree on a definition for early CD to be used in disease-modification trials. The process included literature searches for the relevant basic-science and clinical evidence. A published preliminary definition of early CD was used as the basis for development of a proposed definition that was discussed at the expert opinion meeting. The participants then derived a final definition, based on best current knowledge, that it is hoped will be of practical use in disease-modification trials in CD.
AB - We report the findings and outputs of an international expert opinion process to develop a definition of early Crohn's disease (CD) that could be used in future disease-modification trials. Nineteen experts on inflammatory bowel diseases held an international expert opinion meeting to discuss and agree on a definition for early CD to be used in disease-modification trials. The process included literature searches for the relevant basic-science and clinical evidence. A published preliminary definition of early CD was used as the basis for development of a proposed definition that was discussed at the expert opinion meeting. The participants then derived a final definition, based on best current knowledge, that it is hoped will be of practical use in disease-modification trials in CD.
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U2 - 10.1038/ajg.2012.117
DO - 10.1038/ajg.2012.117
M3 - Article
C2 - 23211844
AN - SCOPUS:84859072629
SN - 0002-9270
VL - 107
SP - 1770
EP - 1776
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 12
ER -