Development of UV-excitable red and near-infrared fluorescent labels and their application for simultaneous multicolor bioimaging by single-wavelength excitation

Tetsuya Mizuno; Keitaro Umezawa; Yutaka Shindo; Daniel Citterio; Kotaro Oka; Koji Suzuki

doi:10.1007/s10895-013-1227-5

Development of UV-excitable red and near-infrared fluorescent labels and their application for simultaneous multicolor bioimaging by single-wavelength excitation

Tetsuya Mizuno, Keitaro Umezawa, Yutaka Shindo, Daniel Citterio, Kotaro Oka, Koji Suzuki

研究成果: Article

7 引用（Scopus）

抜粋

We report a new type of UV-excitable red/NIR-emissive fluorescent dyads (PKF series). Conjugation of a pyrene and a novel bright red/near-infrared (NIR) fluorophore resulted in large quasi-Stokes shift while retaining intense fluorescence emission and sharp spectral bands. Labeling of PKF dyads to biomolecules was performed by means of introduction of a succinimidyl ester. Simultaneous Ca²⁺/albumin dual-color intracellular imaging by PKF in combination with fura-2 (UV-excitable/VIS-emissive Ca²⁺ indicator) reveals its usefulness as a new bioimaging tool.

元の言語	English
ページ（範囲）	1007-1018
ページ数	12
ジャーナル	Journal of Fluorescence
巻	23
発行部数	5
DOI	https://doi.org/10.1007/s10895-013-1227-5
出版物ステータス	Published - 2013 9 1

ASJC Scopus subject areas

Biochemistry
Clinical Psychology
Social Sciences (miscellaneous)
Sociology and Political Science
Spectroscopy
Clinical Biochemistry
Law

文献にアクセス

10.1007/s10895-013-1227-5

フィンガープリント Development of UV-excitable red and near-infrared fluorescent labels and their application for simultaneous multicolor bioimaging by single-wavelength excitation' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

これを引用

Mizuno, T., Umezawa, K., Shindo, Y., Citterio, D., Oka, K., & Suzuki, K. (2013). Development of UV-excitable red and near-infrared fluorescent labels and their application for simultaneous multicolor bioimaging by single-wavelength excitation. Journal of Fluorescence, 23(5), 1007-1018. https://doi.org/10.1007/s10895-013-1227-5

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AU - Citterio, Daniel

AU - Oka, Kotaro

AU - Suzuki, Koji

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