Device Use for Proximal Anastomosis on Ascending Aorta in Off-Pump Coronary Artery Bypass Grafting

Aya Saito, Hiraku Kumamaru, Hiroaki Miyata, Noboru Motomura

研究成果: Article査読

3 被引用数 (Scopus)


Background: We recently reported early postoperative results comparing the use of an anastomosis-assist device with a side-biting clamp for ascending aorta during coronary artery bypass grafting (CABG). Transient neurological complications occurred less often with the device. Here, we evaluated the perioperative safety of the device compared with the aorta no-touch technique (no-touch). Methods: We evaluated patients listed in the Japan Adult Cardiovascular Surgery Database who received isolated off-pump CABG with either the device or the no-touch approach from 2014 to 2016. We performed a one-to-one matched analysis based on a propensity score modeled from patient demographics, comorbidities, cardiac conditions, and procedural characteristics. We compared early outcomes in both groups using Pearson's chi-square or Wilcoxon rank sum test as appropriate; P less than.05 was statistically significant. Results: Among 9546 device and 6890 no-touch patients, we found 5012 patient matches for each group. The device operation time was significantly longer (293 versus 281 minutes; P <.001) and homologous transfusion was significantly greater (56.9% versus 51.0%; P <.001) than with no-touch. Thirty-day operative mortality (1.5% versus 1.7%; P =.34), morbidity and mortality (6.8% versus 7.5%; P =.17), and stroke (0.9% versus 1.1%; P =.36) were similar in both groups. New-onset atrial fibrillation (11.9% versus 10.3%; P =.01) occurred significantly more often with the device. Newly initiated dialysis (1.4% versus 1.9%; P =.051) was more frequent with no-touch whereas reoperation for graft occlusion was more frequent with the device (1.0% versus 0.6%; P =.06) but was not significant for either outcome. Conclusions: The clinical safety of use of the device in CABG was comparable to no-touch for mortality and morbidity. Hemostasis may be a key issue for accomplishing higher-level quality control when devices are used in proximal anastomosis of CABG.

ジャーナルAnnals of Thoracic Surgery
出版ステータスPublished - 2021 6月

ASJC Scopus subject areas

  • 外科
  • 呼吸器内科
  • 循環器および心血管医学


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