Diagnosis of measles viral pneumonia in a patient with Hodgkin's disease by reverse transcription-polymerase chain reaction of serum

Shigehisa Mori, Hiroshi Maruyama, Isao Ito, Michihide Tokuhira, Jun Koide, Tsutomu Takeuchi, Shinji Itoyama, Atsuko Masunaga, Masao Fukushima, Hiroshi Suzuki, Tohru Abe

研究成果: Article査読

1 被引用数 (Scopus)

抄録

We report a case of fatal measles viral pneumonia in a patient with Hodgkin's disease who had no rash. The measles viral cDNA was detected in autopsy tissue from the lung by reverse transcription-polymerase chain reaction. This method was then applied successfully to stored serum. The diagnosis of measles viral pneumonia may be improved by the application of RT-PCR using peripheral blood. Sequence analysis of amplified cDNA suggested the virus infecting this patient was a recent strain, predominantly isolated after 1980. The fatal outcome may have been due to a lack of immune response to the newer strain.

本文言語English
ページ(範囲)327-331
ページ数5
ジャーナルInternational journal of hematology
68
3
DOI
出版ステータスPublished - 1998 10
外部発表はい

ASJC Scopus subject areas

  • 血液学

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