Diagnostic performance of ultrasound without any colon preparation for detecting colorectal polyps in pediatric patients

Takahiro Hosokawa, Mayumi Hosokawa, Yutaka Tanami, Yumiko Sato, Ryosuke Nambu, Itaru Iwama, Eiji Oguma, Yoshitake Yamada

研究成果: Article査読

4 被引用数 (Scopus)

抄録

Background: There are limited data on the sensitivity, specificity and accuracy of ultrasound for detecting colorectal polyps in children and young adults. Objective: To evaluate the diagnostic accuracy of ultrasound, without any colon preparation, for detecting colorectal polyps in pediatric patients and to determine the causes of false-negative results. Materials and methods: We included 74 children with clinical signs like rectal bleeding, abdominal pain or diarrhea who underwent both ultrasound and colonoscopy. We evaluated the diagnostic performance of ultrasound for detecting colorectal polyps before colonoscopy, which served as the reference standard. We used Fisher exact and Student’s t-tests for statistical analyses. Results: Fifteen pediatric patients were diagnosed with colorectal polyps in the transverse (n=3), descending (n=1) and sigmoid (n=6) colon, and rectum (n=5) by colonoscopy. The sensitivity, specificity and accuracy of ultrasound to detect colorectal polyps were 47% (7/15, 95% confidence interval [CI] 21–73%), 100% (59/59, 95% CI 94–100%) and 89% (66/74, 95% CI 80–95%), respectively. The volume (mean ± standard deviation) of polyps not detected by ultrasound was significantly smaller than that detected (270±380 mm3 vs. 4,600±3,900 mm3, P=0.0124). We observed a significant difference in the location between the polyps detected and not detected by ultrasound (rectal/non-rectal=0/7 vs. 5/3, P=0.0256). No significant age or gender difference was observed. Conclusion: The accuracy for detecting colorectal polyps by ultrasound was 89% (95% CI, 80–95%) in our cohort. Polyps found in the rectum and relatively smaller polyps accounted for several false-negative cases.

本文言語English
ジャーナルPediatric Radiology
DOI
出版ステータスPublished - 2019 1 1

ASJC Scopus subject areas

  • 小児科学、周産期医学および子どもの健康
  • 放射線学、核医学およびイメージング

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