Diagnostic value of intestinal fatty acid-binding protein for pneumatosis intestinalis

Shokei Matsumoto, Kazuhiko Sekine, Hiroyuki Funaoka, Tomohiro Funabiki, Motoyasu Yamazaki, Tomohiko Orita, Kei Hayashida, Mitsuhide Kitano

研究成果: Article

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Background Pneumatosis intestinalis (PI) is known as a sign of a life-threatening bowel ischemia. We aimed to evaluate the utility of intestinal fatty acid-binding protein (I-FABP) in the diagnosis of pathologic PI. Methods All consecutive patients who presented to our emergency department with PI were prospectively enrolled. The diagnostic performance of I-FABP for pathologic PI was compared with that of other traditional biomarkers and various parameters. Results Seventy patients with PI were enrolled. Pathologic PI was diagnosed in 27 patients (39%). The levels of most biomarkers were significantly higher in patients with pathologic PI than those with nonpathologic PI (P <.05). Receiver operator characteristic analysis revealed that the area under the curve (AUC) was highest for I-FABP (area under the curve =.82) in the diagnosis of pathologic PI. Conclusions High I-FABP value, in combination with other parameters, might be clinically useful for pathologic PI.

元の言語English
ページ(範囲)961-968
ページ数8
ジャーナルAmerican Journal of Surgery
212
発行部数5
DOI
出版物ステータスPublished - 2016 11 1
外部発表Yes

ASJC Scopus subject areas

  • Surgery

フィンガープリント Diagnostic value of intestinal fatty acid-binding protein for pneumatosis intestinalis' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

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    Matsumoto, S., Sekine, K., Funaoka, H., Funabiki, T., Yamazaki, M., Orita, T., Hayashida, K., & Kitano, M. (2016). Diagnostic value of intestinal fatty acid-binding protein for pneumatosis intestinalis. American Journal of Surgery, 212(5), 961-968. https://doi.org/10.1016/j.amjsurg.2016.04.002