Digital gene atlas of neonate common marmoset brain

Tomomi Shimogori, Ayumi Abe, Yasuhiro Go, Tsutomu Hashikawa, Noriyuki Kishi, Satomi S. Kikuchi, Yoshiaki Kita, Kimie Niimi, Hirozumi Nishibe, Misako Okuno, Kanako Saga, Miyano Sakurai, Masae Sato, Tsuna Serizawa, Sachie Suzuki, Eiki Takahashi, Mami Tanaka, Shoji Tatsumoto, Mitsuhiro Toki, Mami UYan Wang, Karl J. Windak, Haruhiko Yamagishi, Keiko Yamashita, Tomoko Yoda, Aya C. Yoshida, Chihiro Yoshida, Takuro Yoshimoto, Hideyuki Okano

研究成果: Article査読

13 被引用数 (Scopus)

抄録

Interest in the common marmoset (Callithrix jacchus) as a primate model animal has grown recently, in part due to the successful demonstration of transgenic marmosets. However, there is some debate as to the suitability of marmosets, compared to more widely used animal models, such as the macaque monkey and mouse. Especially, the usage of marmoset for animal models of human cognition and mental disorders, is still yet to be fully explored. To examine the prospects of the marmoset model for neuroscience research, the Marmoset Gene Atlas (https://gene-atlas.bminds.brain.riken.jp/) provides a whole brain gene expression atlas in the common marmoset. We employ in situ hybridization (ISH) to systematically analyze gene expression in neonate marmoset brains, which allows us to compare expression with other model animals such as mouse. We anticipate that these data will provide sufficient information to develop tools that enable us to reveal marmoset brain structure, function, cellular and molecular organization for primate brain research.

本文言語English
ページ(範囲)1-13
ページ数13
ジャーナルNeuroscience Research
128
DOI
出版ステータスPublished - 2018 3

ASJC Scopus subject areas

  • 神経科学(全般)

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