Dinucleotide repeat polymorphism in the third intron of the NRAMP2/DMT1 gene

Fumio Kishi, Seitaro Fujishima, Mitsuaki Tabuchi

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Nramp1 (natural resistance-associated macrophage protein 1), encoding a polytropic integral membrane protein, was isolated as a candidate of the mouse Lsh/Ity/Bcg locus, which regulates macrophage activation for antimicrobial activity against intracellular pathogens. The NRAMP2 gene was cloned from human genome as a homologue of NRAMP1. We found a polymorphic dinucleotide repeat in the third intron of the NRAMP2 gene. This polymorphism will be a useful genetic marker to study disease associated with susceptibility to infection with intracellular pathogens.

本文言語English
ページ(範囲)425-427
ページ数3
ジャーナルJournal of Human Genetics
44
6
DOI
出版ステータスPublished - 1999 1 1

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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