Diode Laser Vascular Welding of Swine Aorta Under Scattering Light Monitoring

S. Ohmori, T. Arai, M. Fujita, N. Usami, M. Kikuchi, T. Maehara

研究成果: Conference article査読

2 被引用数 (Scopus)

抄録

Purpose: To develop the catheter-based laser vascular welding device against aortic dissection, we studied fundamental characteristics of the laser vascular welding for aorta dissection model in vitro with the scattering light monitoring to obtain welding proceedings. Methods: We employed the laser vascular welding by means of the combination of the diode laser irradiation and indocyanine green (ICG) stain to the dissected vessel surface in a swine aortic dissection model to obtain localized heat generation on the surface. The forward and backward scattering lights of the diode laser from the welding portion were measured during the laser irradiation. The breaking stresses of the welded aortic pieces were measured. Results: The breaking stress of 170gf/cm2 obtained with the 425W/cm2, 2.4s irradiation may be strong enough to the successful therapy for aortic dissection regarding to the dissecting force caused by blood flow. By analyzing forward and backward scattering lights, we could observe the occurrence of water evaporation in the welding portion, the bleaching of the ICG and the carbonization of the welding portion. Then we could monitor the proceedings of the welding process. The temperature estimation of the welding portion and the microscopic observation revealed that the mechanism of our welding may be basically elastic fiber entwining. Conclusions: We think our vascular welding with the scattering light monitoring of the welding process has the potential to apply catheter-based therapy for aortic dissection.

本文言語English
ページ(範囲)194-198
ページ数5
ジャーナルProceedings of SPIE - The International Society for Optical Engineering
4949
DOI
出版ステータスPublished - 2003 9 30
イベントLasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII - San Jose,CA, United States
継続期間: 2003 1 252003 1 26

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 凝縮系物理学
  • コンピュータ サイエンスの応用
  • 応用数学
  • 電子工学および電気工学

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