Discrimination of normal skin fibroblast and malignant melanocytes using dielectrophoretic force and fluid-induced shear force

Shogo Miyata, Yuta Ojima

研究成果: Conference contribution

抜粋

Cell analysis is an important technology that is widely used for medical diagnosis in hospitals and cell engineering research. Among cell analysis technology, dielectrophoresis (DEP) is one of the most promising approaches for discriminating biological particles because this phenomena requires no labeling procedure with a fluorescent dye or magnetic beads. In this study, we developed a precise cell analysis system by evaluating the DEP force with a liquid flow system. The DEP forces acting on a cell was characterized using a microfluidic chamber containing an electrode-array and fluid-induced shear forces. On the basis of this characterization, the discrimination between healthy skin cells and cancer cells was performed using our novel DEP cell sorting system. As a result, the healthy cells and cancer cells could be distinguished even if the dielectrophoretic properties of those cells were similar.

元の言語English
ホスト出版物のタイトルWorld Automation Congress Proceedings
出版者IEEE Computer Society
ページ109-113
ページ数5
ISBN(電子版)9781889335490
DOI
出版物ステータスPublished - 2014 10 24
イベント2014 World Automation Congress, WAC 2014 - Waikoloa, United States
継続期間: 2014 8 32014 8 7

出版物シリーズ

名前World Automation Congress Proceedings
ISSN(印刷物)2154-4824
ISSN(電子版)2154-4832

Other

Other2014 World Automation Congress, WAC 2014
United States
Waikoloa
期間14/8/314/8/7

ASJC Scopus subject areas

  • Control and Systems Engineering

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  • これを引用

    Miyata, S., & Ojima, Y. (2014). Discrimination of normal skin fibroblast and malignant melanocytes using dielectrophoretic force and fluid-induced shear force. : World Automation Congress Proceedings (pp. 109-113). [6935706] (World Automation Congress Proceedings). IEEE Computer Society. https://doi.org/10.1109/WAC.2014.6935706