In biomolecular communication networks, bacterial cells communicate with each other using a cell-to-cell communication mechanism mediated by diffusible signaling molecules. The dynamics of molecular concentrations in such systems are approximately modeled by reaction-diffusion equations. In this paper, we analyze the ability of cell-to-cell communication systems to attenuate impulsive disturbances with various spatial frequency profiles by computing the integrated squared concentration of molecules. In particular, we perform in-depth study of disturbance responses for an activator-repressor-diffuser biocircuit in the spatial frequency domain to characterize its spatial frequency gain.
|出版物ステータス||Published - 2019 1 1|
|イベント||8th Conference on Foundations of Systems Biology in Engineering, FOSBE 2019 - Valencia, Spain|
継続期間: 2019 10 15 → 2019 10 18
ASJC Scopus subject areas
- Control and Systems Engineering