Droplet network connected by biological nanopores for DNA computing

H. Yasuga, R. Kawano, M. Takinoue, Y. Tsuji, T. Osaki, K. Kamiya, N. Miki, S. Takeuchi

研究成果: Conference contribution

6 被引用数 (Scopus)

抄録

This paper experimentally describes formation of lipid-coated droplet network and demonstrates a biological NAND logic gate using this network and DNA. Droplets which compose this network are comparted by bilayer lipid membranes (BLMs) and connected via biological nanopores of membrane proteins, which ssDNA passes through. In the geometry of the droplet network, four droplets were placed at the corners and the center of an equilateral triangle. Inputs corresponded to the DNA translocation via biological nanopores from the two droplets at the corners (#1 and 2 in Fig. 1) to the center (#3 in Fig. 1), which can be controlled by the applied electrical fields between the droplets. Output was determined by whether DNA translocation occurred through nanopores between the center (#3 in Fig. 1) and the other corner droplet (#4 in Fig. 1). We believe that this system enables direct connection between electrical systems and computing with biomolecules.

本文言語English
ホスト出版物のタイトル2013 Transducers and Eurosensors XXVII
ホスト出版物のサブタイトルThe 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
ページ1221-1222
ページ数2
DOI
出版ステータスPublished - 2013
イベント2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, Spain
継続期間: 2013 6 162013 6 20

出版物シリーズ

名前2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Other

Other2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
国/地域Spain
CityBarcelona
Period13/6/1613/6/20

ASJC Scopus subject areas

  • ハードウェアとアーキテクチャ
  • 電子工学および電気工学

フィンガープリント

「Droplet network connected by biological nanopores for DNA computing」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル