Drug discovery assisted by kinetic target guided synthesis

研究成果: Article査読

抄録

One of the modern medicinal chemistry methods is kinetic target-guided synthesis, where fragment molecules are interacted with a target protein and those in close proximity on the protein spontaneously cross - link by forming a covalent bond. The reactions, which is applicable to the kinetic target-guided synthesis proceed in water and are required no additional reagent. Here, several examples of kinetic target - guided synthesis are described.

本文言語English
ページ(範囲)1245-1246
ページ数2
ジャーナルYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
73
12
出版ステータスPublished - 2015
外部発表はい

ASJC Scopus subject areas

  • 有機化学

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