The E-CELL System (http://www.e-cell.org) is a genetic software package developed, to model not only metabolic pathways but also other higher-order cellular processes such as protein synthesis and signal transduction. Using the system, we have successfully constructed a virtual cell with 127 genes sufficient for 'self-support'. The gene set was selected from the genome of Mycoplasma genitalium, and the metabolisms include transcription, translation, membrane transport, the glycolysis pathway for energy production, and the phospholipid biosynthesis pathway or membrane structure.
|ジャーナル||Annals of Biomedical Engineering|
|出版ステータス||Published - 2000 12 1|
|イベント||2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA|
継続期間: 2000 10 12 → 2000 10 14
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